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KMID : 1039120220110010089
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Clinical and Experimental Vaccine Research
2022 Volume.11 No. 1 p.89 ~ p.95
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Factors associated with side effects of COVID-19 vaccine in Indonesia
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Wibowo Johan
Heriyanto Rivaldo Steven
Wijovi Felix
Halim Devina Adella
Claudia Claudia
Marcella Elizabeth
Susanto Billy
Indrawan Michele
Heryadi Nadia Khoirunnisa
Imanuelly Michelle
Anurantha Jonathan Juniard
Hariyanto Timotius Ivan
Marcellin Chintya
Sinaga Terry Devita
Rizki Saraswati Anindita
Sieto Novia
Siregar Jeremia Immanuel
Lugito Nata Pratama Hardjo
Kurniawan Andree
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Abstract
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Purpose: As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic.
Materials and Methods: This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval.
Results: A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263?0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263?0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401?12.701) and immune reactions (OR, 3.375; 95% CI, 1.356?8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321?16.409).
Conclusion: Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
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KEYWORD
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COVID-19, Vaccination, Vaccines, Side effect
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